Myrtle Mae Simmons: The daughter of Veta Simmons, Myrtle Mae is in her early twenties and still unmarried, a source of concern to her mother.
Veta Simmons: Myrtle Mae's mother and Elwood's sister, Veta considered herself a member of the "better society" of their small town and is a member of the Wednesday Forum, a social club for the ladies of the town. She is, however, slightly embarrassed by her brother.
Elwood P. Dowd: Veta's brother, Elwood is forty-seven years old and owns the family home he lives in with Myrtle and Veta. He is pleasant, loveable, and a friend to everyone. He enjoys his visits to the neighborhood bar, but is by no means a drunk.
Miss Johnson: The maid
Mrs. Ethel Chauvenet: Sixty-five years old, Mrs. Chauvenet is wealthy and a member of the Wednesday Forum. She also has a marriageable grandson about Myrtle's age.
Ruth Kelly, R.N.: Twenty-four yeas old and pretty, Ruth is head nurse at Chumley's Rest, a sanitarium for mental patients.
Duane Wilson: About twenty-eight years old, large, and muscular, Duane is the sanitarium's attendant and strong arm. He admires Dr. Chumley, perhaps excessively.
Dr. Lyman Sanderson: A young doctor of psychiatry, Dr. Sanderson is quite attractive and has caught the Ruth's eye.
Dr. William R. Chumley: In his late fifties, Dr. Chumley is the head of Chumley's Rest. He is a confident, sometimes pompous, man.
Betty Chumley: Dr. Chumley's wife, Mrs. Chumley is a lovely woman about fifty-five years old.
Judge Omar Gaffney: An elderly lawyer, Judge Gaffney represents the estate of Veta and Elwood's late mother.
E.J. Lofgren: An ultimately wise cab driver