Oscar Madison – A disorderly mess of a man, and a recently divorced sportswriter.

Felix Ungar – A finicky, fussy hypochondriac with his own marriage struggles who moves in with Oscar.

Speed – One of Oscar and Felix’s poker buddies; he is crusty and sarcastic.

Murray – One of the poker buddies; a NYPD policeman.

Roy – One of the poker buddies; Oscar’s accountant; he has a dry sense of humor.

Vinnie – One of the poker buddies; he is subdued and picked-on by Speed.

Gwendolyn and Cecily Pigeon – English sisters who are Oscar’s upstairs neighbors.